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Comment & Response
August 25, 2015

Opioid Dependence Treatment in the Emergency Department

Author Affiliations
  • 1Yukon Kuskokwim Health Corp, Bethel, Alaska
JAMA. 2015;314(8):834-835. doi:10.1001/jama.2015.8519

To the Editor In the article about emergency department (ED)–initiated buprenorphine/naloxone treatment for opioid dependence, Dr D’Onofrio and colleagues1 omitted important information and then focused on the most optimistic outcomes to infer a benefit.

First, drug trials should monitor and report harms of treatment. Yet the authors made no mention of harms. Was there any mortality? Were there any overdoses or adverse drug reactions?