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Verrucae, and particularly those of the juvenile flat type, often present a therapeutic problem that is hard to solve. The remedies that have been suggested are legion—curettage, electrolysis, radium, roentgen ray, fulguration, caustics of various kinds, carbon dioxide snow, salicylic acid, sulphur, sulphurated potassa and numerous others.
Internally, C. J. White found yellow mercurous iodide helpful; Jadassohn has long advocated arsenic; Colrat of Lyons was first to suggest magnesium sulphate, and many practitioners have prescribed nitrohydrochloric acid with success.
In deciding on the character of the local application to he used, care must be exercised to select something that will not cause permanent scarring; otherwise, the result may be worse than the disease. I have known of many a reputation damaged by so slight a thing as this.
In 1922, Siemens found arsphenamine, dissolved in physiologic sodium chloride solution, and injected directly into the lesions, curative in a large percentage
Sutton RL. SULPHARSPHENAMINE IN THE TREATMENT OF WARTS. JAMA. 1926;87(14):1127. doi:10.1001/jama.1926.92680140001012a
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