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Article
June 3, 1933

THE LIFE CYCLE OF THE TUBERCLE BACILLUS

Author Affiliations

Pittsburgh
Director, Institute of Pathology, Western Pennsylvania Hospital

JAMA. 1933;100(22):1794. doi:10.1001/jama.1933.02740220060033

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Abstract

To the Editor:  —In The Journal, April 29, page 1342, is a brief review of our studies on the tubercle bacillus (Mellon, R. R.; Richardson, R. D., and Fisher, L. W.: Proc. Soc. Exper. Biol. & Med.30:80 [Oct.] 1932. Lindegren, C. C., and Mellon, R. R., ibid.30:110 [Oct.] 1932. Mellon, R. R.; Richardson, R. D., and Fisher, L. W.: J. Bact.24:45 [Jan.] 1933). I feel sure that the reviewer did not intend to leave the impression that we had postulated the existence of morphologically distinct male and female sex cells. But since this impression has been conveyed to me from others, permit me to interpret these studies as follows: The sexual mechanism suggested (not proved) is that of an autogamous fusion (Lindegren, C. C., and Mellon, R. R.: J. Bact.25:47 [Jan.] 1933), one of the lowest orders of sexuality, in contrast to

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