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Article
November 6, 1926

INTERSTITIAL KERATITIS IN CONGENITAL SYPHILIS: CLINICAL NOTES ON INCIDENCE AND TREATMENT

JAMA. 1926;87(19):1551-1555. doi:10.1001/jama.1926.02680190027008
Abstract

In the free dispensary of the University of Pittsburgh, 1920 to 1925 inclusive, there were admitted approximately 30,000 new cases. Of these, about half were received in the department of ophthalmology. The large proportion of eye cases is accounted for by the fact that the department of ophthalmology, which includes the outpatient department of the Pittsburgh Eye and Ear Hospital, was the original unit of the present organization, other branches of medicine being represented after 1919. As the care of syphilis has been centralized in the department of dermatology, we have enjoyed an unusual opportunity for the observation and treatment of syphilis complicated by eye lesions. A diagnosis of syphilis was made and treatment instituted in 2,536 cases. The incidence of syphilitic eye lesions among 15,000 eye cases and 2,536 syphilitics is given in table 1.

Of interstitial keratitis, 150 cases occurred in congenital syphilis; seven patients were suffering from

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