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July 22, 1933


JAMA. 1933;101(4):301. doi:10.1001/jama.1933.02740290049031

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To the Editor:  —In The Journal, June 3, appeared a paper on this subject by Freeman, Fong and Rosenberg.I have always emphasized that in most instances deteriorated, demented patients will not go into a remission and will not improve. Early in my work the malarial type of fever curve was abandoned as a model. Long sustained temperatures with a high plateau ranging above 103.5 F. for eight hours and above 105.8 and not exceeding 107 for four hours, have been employed and recommended by us for at least two years. I will return to the rationale of this a little later.The average number of treatments has not been confined to ten or twelve. On the contrary, I believe that the number of treatments necessary to obtain results in a case of dementia paralytica average about twenty. Most remissions take place after the fifteenth, twenty-fifth and thirty-fifth treatment. I

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