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Article
December 11, 1926

GLANDULAR FEVER (INFECTIOUS MONONUCLEOSIS)

JAMA. 1926;87(24):2000-2001. doi:10.1001/jama.1926.02680240044018
Abstract

Modern medicine can cite a number of instances of the unquestionable advantage of calling attention to groups of symptoms or symptom-complexes that are either rare or of debated import. The inevitable consequent focusing of consideration on the problems concerned is likely to lead to the recognition of many similar instances, so that the feature of rarity is presently lost. This has been true, for example, in the case of the Stokes-Adams syndrome, which has become a familiar entity in practice. Discussions of uncertainties of diagnosis and etiology tend to elicit new features of clinical, pathologic or bacteriologic import that may presently transform debatable phenomena into a fabric of dependable knowledge. From this standpoint in particular it is significant to find renewed interest manifested in what has long been described as glandular fever since the pioneer account of E. Pfeiffer 1 in 1889. It refers to an acute, seemingly infectious disease

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