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December 25, 1926


JAMA. 1926;87(26):2164-2165. doi:10.1001/jama.1926.02680260032015

The treatment of neurosyphilis by fever-producing methods, notably by the genesis of malaria in the patients, cannot longer be classed as a novelty. The cases under observation are already numbered by the hundreds, so that it becomes desirable to take account of the outcome from time to time. The problem under consideration is complicated by the admitted fact that spontaneous remissions of the principal symptoms are known to occur, so that some improvement may be expected under practically all forms of treatment. Nothing less than the statistics of a large number of patients in observations extending over periods of time that are measured by years rather than months will justify anything more than tentative conclusions. Nevertheless, the discussion 4 at the golden anniversary meeting of the American Dermatological Association in Philadelphia a few months ago gives encouraging indications of the value of the von Jauregg method in the treatment of