In a contribution published in 1921, I 1 called attention to the frequency of the occurrence of symptoms of the infection in apparently healthy persons who were found to be carriers of Endameba histolytica, and since that time I have taken the opportunity, whenever possible, of checking the clinical history of all persons who have, to my personal knowledge, been determined to be carriers of this parasite. My observations along this line have proved the truth of the statements contained in the publication referred to, and have shown that a very large proportion of carriers of Endameba histolytica do present symptoms of the infection, and are thus not true carriers in the sense that they are free from any symptoms of infection. Experience has shown that more than 50 per cent of so-called carriers of this parasite present some symptoms apparently caused by its presence in the intestine, and it
CRAIG CF. THE SYMPTOMATOLOGY OF INFECTION WITH ENDAMEBA HISTOLYTICA IN CARRIERS. JAMA. 1927;88(1):19–21. doi:10.1001/jama.1927.02680270019005
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