[Skip to Content]
[Skip to Content Landing]
Article
August 19, 1933

PELLAGRA: REVIEW OF CASES WITH SPECIAL REFERENCE TO THE GASTRIC SECRETIONS

Author Affiliations

UNIVERSITY, VA.; SEATTLE
From the Department of Internal Medicine, University of Virginia Department of Medicine.

JAMA. 1933;101(8):576-580. doi:10.1001/jama.1933.02740330008003
Abstract

Recent studies in which particular attention has been given to the gastric secretions in pellagra are those of Givens,1 Guthrie2 and Boggs and Padget.3 In addition, Bloomfield and Polland,4 in a recent monograph on gastric anacidity, have tabulated the observations of several other authors whose studies were based on smaller series of cases. Givens1 studied the gastric acid values following Ewald meal stimulation in 100 pellagrins, twenty-four of whom were children. Anacidity was found in 39 per cent of his cases, but its occurrence apparently bore no relationship either to age or sex or to the duration and recurrences of the disease. Guthrie,2 in a larger series, found an absence of hydrochloric acid in 68.9 per cent and 62.8 per cent of all of his cases, and in 67.5 per cent of forty patients in whom histamine had been used as a stimulant to

×