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January 15, 1927

THE DISABILITIES CAUSED BY HYPOPHYSECTOMY AND THEIR REPAIR: THE TUBERAL (HYPOTHALAMIC) SYNDROME IN THE RAT

Author Affiliations

Associate Professor of Anatomy, Stanford University School of Medicine PALO ALTO, CALIF.

JAMA. 1927;88(3):158-161. doi:10.1001/jama.1927.02680290020005
Abstract

From results gained in an extensive series of investigations on the dog carried out in 1922 and earlier, Camus and Roussy, 1 and Bailey and Bremer 2 concluded that the hypophysis exercises few of the functions that have been attributed to it. Camus and Roussy state, in answer to the question, What is the proper function of the hypophysis? "We would not know how to reply except by hypotheses." Bailey and Bremer likewise affirm, "But we must admit that we have little actual knowledge of its functional significance in the adult animal." Other investigators have in most cases considered that the so-called pituitary disorders, including obesity and not infrequently glycosuria and polyuria, are due to their operatively induced pituitary deficiency. Recently Roussy 3 has been will

ing to grant that the rôle of the anterior pituitary in skeletal growth is well established, and Bremer 4 states that the pituitary is

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