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September 2, 1933


JAMA. 1933;101(10):790-792. doi:10.1001/jama.1933.02740350048021

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Research on the Respiratory Ferment  In continuing his research on the respiratory ferment, Otto Warburg has made a discovery, on which he reports in the Biochemische Zeitschrift. He has succeeded in getting the respiratory ferment, the existence of which could heretofore be proved only indirectly, on a suitable object directly under the spectroscope, and thus to render it visible. By means of an ingenious indirect method, Warburg had, as it were, determined the chief properties and the spectrum of the respiratory ferment. There is, namely, an inactive union with carbon monoxide, as in hemoglobin. This compound, however, is easily decomposed by light and thus the respiratory ferment again becomes active. In this restoration of the action, only those portions of the light can act that are taken up and absorbed. By ascertaining through a test which portions of the light rays are active, Warburg was able to determine indirectly the

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