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The previous edition of this excellent standard textbook was published in 1920. In the present volume many changes have been necessary; others, desirable. Among the latter is a decrease in bulk of nearly 250 pages. This has been made possible by the omission, or relegation to small type, of considerable material on chemistry and anatomy. At present, instruction in the ancillary sciences furnishes an adequate groundwork in such subjects. In the rearrangement of chapters, additional space has been saved. This reduction in bulk is the more remarkable when one considers the vast amount of new material which recent research has made it necessary to include. For instance, the third edition of this work was published two years before Banting and Best, working in Macleod's laboratory, isolated insulin. Moreover, the word "thyroxin," with Kendall's probable formula for it, does not appear in the older edition; and the work of Collip on
Principles of Human Physiology. JAMA. 1927;88(5):345. doi:10.1001/jama.1927.02680310057032
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