For some time, even at our large eastern lying-in hospitals, the conclusion has persisted that the chemical examination of the blood gives no significant data in eclampsia. We have been distinctly lacking in any sort of a logical formula based on specific observations in the treatment of these desperate cases. The tedium of the program of sweating and venesection with general stimulation of the emunctories was a tax on all concerned, because of the prolonged period of anxiety, during which the safety of both mother and child were in extreme jeopardy. Further, its consummation awaited spontaneous delivery, during which time the mother frequently lost that for which she entered the obstetric lists. Various methods of treatment, intravenous and otherwise, have been utilized, but always with a distinct maternal and fetal mortality. The use of glucose has been more or less empiric, based on the disturbance of the carbohydrate metabolism of
WILSON HP. CARBON DIOXIDE COMBINING POWER AS BASIS FOR TREATMENT IN ECLAMPSIA: WITH PARTICULAR REFERENCE TO THE USE OF SODIUM BICARBONATE. JAMA. 1927;88(6):380–382. doi:10.1001/jama.1927.02680320016004
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