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February 5, 1927

Histological Technique: For Normal Tissues, Morbid Changes and the Identification of Parasites.

JAMA. 1927;88(6):428. doi:10.1001/jama.1927.02680320064036

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This is not a mere book of methods but a document with a point of view that should be understood by all who study and all who make histologic preparations. There has not been anything like it since Mann's Methods and Theory of Physiological Histology, and it does justice to the progress of the last quarter century. In the discussion of the structure of protoplasm and the effects of fixation is seen the influence of Bayliss and the authors of "General Cytology" (Cowdry). The gulf that separates the methods of studying organs and tissues from those adapted to the study of cells is well portrayed and should help to eliminate meaningless phrases such as "cells with granular protoplasm" from the literature. The chapter on the theory of staining is good as far as it goes but does scant justice to the adsorption theory. The distinctive physical properties of different gels

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