This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.
Acute gonorrhea is a generalized inflammation of the mucous membrane of the anterior urethra resulting from the presence of gonococci and the toxic products. The degree of the extension to the posterior urethra or deep into the submucous tissues of the anterior urethra varies directly with the successful control during the early stages of the infection. Various percentages of the extension into the posterior urethra are given by different authors, but it is stated in many text-books on gonorrhea that as high as 75 per cent become posterior. It is doubtful whether such a high proportion become posterior in the present experience of urologists, but in our observations previous to the use of the present method, it seemed highly frequent.
It is generally realized that the organotropic index of a drug must be considered as well as the gonococcidal index in determining the fitness of the drug for local treatment.
HERROLD RD, CULVER H. THE TREATMENT OF ACUTE GONORRHEA WITH ANTISEPTICS IN GELATIN. JAMA. 1927;88(7):459–460. doi:10.1001/jama.1927.02680330011004
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: