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September 30, 1933


JAMA. 1933;101(14):1095. doi:10.1001/jama.1933.02740390053026

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To the Editor:  —I have recently had several striking experiences in doing Aschheim-Zondek tests on rabbits, and in doing one blood transfusion with a diabetic donor. So far as I know there are no published reports of similar experiences and my reason for recording them is to sound a warning to those doing blood transfusions, that they may avoid similar and possibly fatal accidents.About one year ago I had occasion to perform an Aschheim test for suspected pregnancy. I used the technic that I had previously used in many instances, by injecting about 8 cc. of freshly voided urine into the marginal vein in the ear of a rabbit. On this occasion after a little more than half of the urine had been injected the rabbit was taken with a convulsive seizure and was dead immediately. I secured a second specimen of urine, this time doing a chemical analysis

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