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October 28, 1933


JAMA. 1933;101(18):1394-1395. doi:10.1001/jama.1933.02740430040014

At the recent session of the American Medical Association, in a discussion before the Section on Gastro-Enterology and Proctology, Gorham1 said: "The subject of vitamins and their relation to the so-called deficiency diseases has become so complicated that most of us are unable to follow the course of events related to this field with any degree of orientation." Vitamin D and irradiated ergosterol were at first the subject of widely varying claims and counterclaims. Today the advantages and limitations of the vitamin D carrying substances are rather well established. Now confusion and exaggeration distort our views of vitamin A and its precursor carotene. Some manufacturers promote vitamin A and carotene products without regard to lack of substantiation for the claims that are made.

From the accumulating investigative evidence it seems almost certain that carotene may be converted in the liver to vitamin A. Thus all the claims of physiologic

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