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March 19, 1927


JAMA. 1927;88(12):939-940. doi:10.1001/jama.1927.02680380063028

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Filtrable Types of Bacilli  Recent researches are adding constantly to the number of micro-organisms which possess, in addition to their recognized normal morphology, an invisible or microscopic type capable of traversing porcelain filters and designated as sporular, for the want of a more accurate term. Dr. Arloing of Lyons agrees in his conclusions with Dr. Vaudremer, of the Pasteur Institute of Paris, that there are filtrable types of the tubercle bacillus. Carefully filtered cultures of that organism have produced tuberculosis with frank bacilli in animals protected since birth from any possible outside contagion. The same observations have been made on the dysentery bacillus, and just recently M. Hauduroy has added the diphtheria bacillus to the list. In a communication addressed to the Academy of Sciences, he has pointed out that, by utilizing a diphtheritic toxin obtained by filtration and lacking any micro-organism visible on ultramicroscopic examination, cultures are obtainable from

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