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November 4, 1933


JAMA. 1933;101(19):1492-1493. doi:10.1001/jama.1933.02740440052021

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Procaine Hydrochloride in the Treatment of Rheumatism  The medical profession is indebted to Professor Leriche of Strasbourg for a method of treatment for sprains and mild luxations, which consists in injecting a cubic centimeter of a solution of procaine hydrochloride (1: 1,000) at the level of the painful areas. The anesthesia thus secured suppresses the reflex that supports the contracture of the ligaments. A person with a sprain thus treated can walk immediately after the injection. Schulmann and Benassy have applied this method to persons with rheumatic joint pains with complete success. Even in cases of chronic arthritis, the injection of procaine at the insertions of the ligaments and the articular tendons brought about quickly not only relief from the pain but also restoration of the movements. The procedure has more chance of success when the functional disorders are more significant and the articular lesions are more discrete. To explain

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