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April 2, 1927

Special Article

JAMA. 1927;88(14):1078-1079. doi:10.1001/jama.1927.02680400034013

CEREBROSPINAL FLUID IN DIFFERENTIAL DIAGNOSIS*  FRANK FREMONT-SMITH, M.D.ANDJAMES B. AYER, M.D.BOSTONWe present a chart of cerebrospinal fluid examinations which we believe is helpful in differential diagnosis. While they are based on exact statistics, the figures that are given are not averages but estimated values.No attempt at a comprehensive survey was made, and many diseases and conditions in which the observations are of doubtful value or in dispute are not included. The object has been, rather, to correlate data about the fluid in group manner, the groupings representing diseases in which clinical differential diagnosis is difficult, or, on the other hand, groups in which the spinal fluid is similar.The method of presentation is obvious. The use of heavy type is designed to stress the most significant tests in a given disease. The data are presented on three cards measuring 9¼ by 11¼ inches, which are