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April 2, 1927


JAMA. 1927;88(14):1092. doi:10.1001/jama.1927.02680400048022

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Local Autovaccination in the Treatment of Gonorrhea  Dr. Darget has presented to the Société française d'urologie a special method of treating acute gonorrhea. It consists in planting in the urethra, in the form of injections, or combined with a fusible plug, an autovaccine (a bouillon vaccine) prepared from the cultivated gonococcus and sterilized, with from 30 to 50 million micro-organisms per cubic centimeter. Fifteen applications seem to be the necessary dose. Of thirty-three patients thus treated, twenty-nine recovered completely. In the four patients who were not cured by the one course of treatment, the disease disappeared following a few slight antiseptic injections, which would not have sufficed under ordinary circumstances. The action of the vaccine is entirely local and it is not held that it confers any immunity against later infections.

The New Actinologic Institute in Paris  A special institute of actinology located in the Vaugirard quarter of Paris (6

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