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To the Editor:
—Several articles have appeared recently, dealing with healing of muscle to fibrous tissue. Many years ago I did experiments involving this problem; the divergence of results is due to the fact that the authors are not dealing with the same thing.Seelig and Chouke (Fundamental Factor in Recurrence of Inguinal Hernia, Arch. Surg. 7:553 [Nov.] 1923) and Seelig (Fundamental Principles Underlying the Operative Cure of Inguinal Hernia, The Journal, Feb. 19, 1927, p. 529) find that there is no union between muscles and fibrous tissue, while Koontz (Surg. Gynec. Obst. 42:222 [Feb.] 1926) finds that there is union. Both are right.Several fundamental factors in wound healing must be kept in mind. Fibrous tissue alone can form a union. Any fat-bearing tissue prevents healing because fibrin bundles cannot form in the presence of fat. Muscle fibers do not heal; it is only the perimysium that
Hertzler AE. HEALING OF MUSCLE TO FIBROUS TISSUE. JAMA. 1927;88(14):1098–1099. doi:10.1001/jama.1927.02680400054033
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