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In 1913, Aschoff and Landau gave the name reticuloendothelial system to a type of cells distributed throughout the body which have certain morphologic and functional similarities. These cells are mesenchymal elements which have the property of storing up certain dyes, such as trypan blue, and comprise the endothelial cells of the blood and lymph vessels, the fibrocytes or ordinary connective tissue cells, the reticulum cells of the spleen pulp and lymph nodes, the histiocytes and other cells. Benda reviews the entire literature on the reticulo-endothelial system and gives the results of his own extensive experimental and clinical studies. He discusses the uranin method, the hemolysin reaction and the bromine method as functional tests of the capillary endothelium during pregnancy, and he chooses the permeability of the meninges as the criterion. He likewise reviews the Rosenthal test, the congo red method and the urobilinemia index as functional tests of the reticulo-endothelial
Das reticulo-endotheliale System in der Schwangerschaft:. JAMA. 1927;88(14):1103. doi:10.1001/jama.1927.02680400059038
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