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Article
January 10, 1931

COMPARATIVE BIOLOGIC AND HISTOLOGIC STUDY OF LYMPH GLANDS FROM SYPHILITIC PATIENTS

Author Affiliations

PHILADELPHIA
From the Research Institute of Cutaneous Medicine.

JAMA. 1931;96(2):98-100. doi:10.1001/jama.1931.02720280016005
Abstract

Several investigators have studied the inguinal lymph glands removed from patients with syphilis. In each case the phase studied was somewhat different from the other. Our object in the present study has been to correlate the finding of Spirochaeta pallida in inguinal lymph node sections by the silver impregnation staining method and, with the biologic method, by injecting an emulsion from the same lymph node into rabbit testes. By this correlation we hoped to throw some additional light on the morphology, the efficiency of our staining methods, the importance of the biologic method for diagnosis and, in an indirect way, something about the transmissibility of Spirochaeta pallida.

MATERIAL AND METHOD OF STUDY  Inguinal lymph glands were removed from twenty-one patients with untreated syphilis. In all the patients the Kolmer-Wassermann and Kahn reactions were strongly positive, and, in addition, most of them had some clinical manifestation of syphilis. The excised lymph

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