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April 9, 1927

Ueber Fortschritte in der Behandlung des Krebses.

JAMA. 1927;88(15):1202. doi:10.1001/jama.1927.02680410078035

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The author discusses progress in the treatment of cancer, disclaiming the justification of extreme pessimism in judging the remote results of cancer therapy. He expresses the conviction that the body contains defensive forces which occasionally are strong enough to overcome not only solitary cancers but also metastases. The future of successful therapy lies in the endeavor to utilize and reenforce these natural defensive forces. For his experimental studies he used cancers produced by inoculation because epithelioma following consistent tar irritation did not show satisfactory uniformity. While it is admitted that the results of observation and treatment in animals cannot indiscriminately be applied to cancer in man, still in the later stages the cancerous conditions in animals become practically identical with those to be found in spontaneous cancers in the human being. The efficacy of radiotherapy is not exhausted by the direct action on malignant cells but also produces changes in

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