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November 25, 1933

The Therapeutic Agents of the Quinoline Group: Cinchophen, Plasmoquine, Nupercaine, Quinine and Acridine Dyes; the Relation Between Their Chemical Constitution and Pharmacologic Action.

JAMA. 1933;101(22):1750. doi:10.1001/jama.1933.02740470064032

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Chemical agents derived from the quinoline nucleus have found wide usage in therapeutics. Such common and well known drugs as quinine and its derivatives, oxyquinoline sulphate, cinchophen, nupercaine and the acriflavines are related to quinoline. With the exception of quinine and its naturally occurring chemical relations, most of the drugs in the quinoline group are the result of laboratory investigation. Many of them have been produced and found their usefulness since the World War. The chemical and the pharmacologic and therapeutic literature on this group of drugs of diverse use is widely scattered in the chemical, pharmacologic and medical literature. Dr. von Oettingen has made a worth-while contribution to the literature of chemistry, pharmacology and therapeutics by collecting between two covers this widely scattered information. The book, however, is not a mere compilation of data. It is a careful attempt to correlate, whenever the data permit, the ground already gained

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