The early reports on the action and uses of ephedrine 1 indicated that it should be a valuable remedy for the relief of attacks of bronchial asthma in children as well as in adults.
The first work revealed that ephedrine was effective when given orally, and that the relief given often lasted as long as twenty-four hours and seldom less than four hours. As far as could be determined, a tolerance for the drug was not established.
During the last few months we have used ephedrine sulphate in the treatment of twenty-two cases of bronchial asthma in children. Twenty of these were taken from private practice, and two from the outpatient dispensary of the Children's Memorial Hospital. The effects of the drug were observed and reported to us in each instance by the parents. They were requested to keep a record of the dose; whether relief was afforded; if so,
MUNNS GF, ALDRICH CA. EPHEDRINE IN THE TREATMENT OF BRONCHIAL ASTHMA IN CHILDREN. JAMA. 1927;88(16):1233. doi:10.1001/jama.1927.02680420023009
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