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News From the Food and Drug Administration
October 20, 2015

Easing Cancer Chemotherapy Effects

JAMA. 2015;314(15):1554. doi:10.1001/jama.2015.13011

The FDA approved a new drug last month to help prevent delayed-phase nausea and vomiting in patients undergoing cancer chemotherapy.

Rolapitant, marketed as Varubi, was approved for use by adults in combination with other antiemetic drugs (http://1.usa.gov/1EBmeA2). Nausea and vomiting are common among patients with cancer who receive chemotherapy, sometimes persisting for days following treatment. Delayed-phase nausea and vomiting is defined as occurring from 24 hours to up to 120 hours after the start of chemotherapy.