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April 23, 1927


Author Affiliations

From the medical service of Dr. Thomas McCrae and the Department for Diseases of the Chest, Jefferson Hospital.

JAMA. 1927;88(17):1301-1302. doi:10.1001/jama.1927.02680430003002

There is perhaps no manifestation of disease which arouses so much concern as hemorrhage. It points without question to the presence of diseased or injured tissue, and not infrequently life depends on the early recognition of the cause and its effective control. When superficial structures are involved, ligation, cautery, pressure and local hemostatic agents are usually efficient means of therapy. However, in hemorrhage from internal sources these are of doubtful value, obviously because certain parts are inaccessible or unsatisfactory for local treatment. Furthermore, the general condition of the patient may not justify surgical intervention. It may be wiser to utilize conservative measures and to aid the normal protective mechanisms of the body.

A mechanism of great importance is that of blood coagulation. Failure of this mechanism to function normally may lead to prolonged and fatal bleeding. It is well, therefore, always to consider its efficiency, whether or not surgical methods