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December 9, 1933


JAMA. 1933;101(24):1857-1859. doi:10.1001/jama.1933.02740490017004

For more than twenty years the laboratory with which I am associated (as many other laboratories) has studied necropsy material to determine the relation between x-ray densities and pathologic observations. It is my opinion that the relative degrees of scar tissue and pulmonary exudate can be determined from a study of x-ray films with sufficient accuracy to be of great practical value in the diagnosis, prognosis and treatment of pulmonary tuberculosis.

Pulmonary tuberculosis can be understood more easily if the various lesions are regarded as the products of inflammation and if it is remembered that tuberculous infection varies from marked chronicity to severe activity. Thus, the densities as shown on the x-ray film reveal lesions that vary from dense scar tissue (proliferative type) to extensive pulmonary exudate (exudative type).

The study of a case of pulmonary tuberculosis necessitates determining not only the extent and location of the lesions but also

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