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January 4, 1941


Author Affiliations

Trenton, N. J.

JAMA. 1941;116(1):70. doi:10.1001/jama.1941.02820010072028

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To the Editor:—  In a recent issue of the American Journal of the Medical Sciences (199:539 [April] 1940) there is a report by C. H. Brown on the role of foci of infection in the pathogenesis of arthritis entitled "Foci of Infection in Psychiatric Patients." The author compared the incidence of such foci in a group of arthritic patients with the incidence of foci of infection in a group of "healthy" controls. He found that there was no essential difference in the incidence of foci of infection in the two groups and drew the conclusion, therefore, that foci of infection did not constitute a sufficient factor in the pathogenesis of arthritis and that another factor was necessarily involved, such as a constitutional hereditary predisposition to arthritis or a state of allergy to the bacteria in the foci. This conclusion appears valid and logical enough until one considers his so-called

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