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Comment & Response
October 27, 2015

Medical Use of Cannabinoids

Author Affiliations
  • 1Foundation for Ethics in Pain Care, Bellevue, Washington
JAMA. 2015;314(16):1751. doi:10.1001/jama.2015.11435

To the Editor Dr Whiting and colleagues1 presented the results of a systematic review and meta-analysis of medical cannabinoids, claiming moderate-quality evidence supporting their use for chronic pain and spasticity. The studies on which they relied included investigations of numerous preparations with varying routes of administration. The products considered each have their own unique pharmacodynamics.