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To the Editor:
—In The Journal, April 9, p. 1142, in an interesting paper on oral lesions, Bloodgood says that "leukoplakia, or white patches in the mouth, is caused by tobacco and tobacco only."In many instances, syphilis causes both leukoplakia and leukokeratosis in nonsmokers.In the greater part of Africa, in Asia and in the Far East, leukoplakia and leukokeratosis are caused by the habit of keeping in the buccal cavity a bolus composed of betel-nut, lime and a leaf.Leukoplakia of the introitus vaginae is probably caused by irritating secretions.Figure 5, marked geographic tongue, represents an instance of "glossite lozangique médiane." So-called geographic tongue is a fugacious lesion, of which the synonyms are transitory benign plaques of the tongue, and erythema migrans linguae.
Wise F. LEUKOPLAKIA. JAMA. 1927;88(18):1437. doi:10.1001/jama.1927.02680440071035
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