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December 23, 1933


Author Affiliations

From the Department of Obstetrics and Gynecology, State University of Iowa College of Medicine.

JAMA. 1933;101(26):2020-2023. doi:10.1001/jama.1933.02740510012003

There have recently appeared several reports on gestational polyneuritis (neuronitis), emphasizing the clinical and pathologic aspects of this little known disease (Berkwitz and Lufkin,1 Wilson and Garvey,2 McGoogan,3 Hoffman4 and Strauss and McDonald5). Having seen twelve certain or probable cases within the past seven years, we are persuaded that the condition is not so rare as is generally thought and that a wider knowledge of the essential clinical picture will increase the frequency with which the diagnosis is made and will proportionately diminish the number of patients reported as succumbing to "late toxic vomiting of pregnancy." It is our purpose to discuss particularly the clinical observations in the light of the recorded cases and of our own experience.

ETIOLOGY  It has been commonly assumed that the disturbance is the direct result of the action of a toxin which is elaborated by the product of conception