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To the Editor:
—It is surprising how few in the medical profession, as well as among the laity, know of the high phenolphthalein content of one of the emulsions of liquid petrolatum marketed under the name of "Agarol." The impression gained from the advertising matter and the circulars supplied by the manufacturers of the preparation is that it represents merely a mixture of mineral oil and agar. The label on the bottle exhibits the words "mineral oil" and "agar agar" in large type, and the word "phenolphthalein" in minute letters. Little wonder that the latter ingredient is generally overlooked. Physicians advising its use, as well as patients using it, do not realize that they are being weaned away from the use of pills or tablets containing phenolphthalein as their active ingredient, to the use of this liquid, which contains phenolphthalein in considerable dosage.The composition of the preparation was reported
Sagal Z. PHENOLPHTHALEIN AND AGAROL. JAMA. 1927;88(19):1502. doi:10.1001/jama.1927.02680450046030
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