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Article
January 18, 1941

La sénescence et le rajeunissement

JAMA. 1941;116(3):261-262. doi:10.1001/jama.1941.02820030083036

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Abstract

The author discusses senescence and rejuvenation and goes into details on how to avoid the former and effect the latter. He analyzes the problem of senescence, of extinction of life and of final death. He recalls that growth and maturity, cicatrization, cure and regeneration, even sensation and perception, are manifestations of cellular interactivity. Senescence begins in the cell and ends in death, which is nothing else but the disintegration of the edifice formed by the cells. Protozoans know neither old age nor death. Under suitable surroundings they are capable of indefinite reproduction. Each individual protozoan achieves its existence by fission. Metazoa know neither senescence nor death. The life of certain of these organisms may be without limit (jellyfish, corals, hydras and hydroid polyps). Certain cells can survive the death of the organism for long periods. Thus a mouse may live for two months, but the cells of its tegument or

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