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May 14, 1927


Author Affiliations

From the Division of Applied Therapy, Bureau of Laboratories Department of Health, New York City.

JAMA. 1927;88(20):1552-1554. doi:10.1001/jama.1927.02680460022005

The literature on encephalitis associated with measles is meager and rather indefinite. The ideas with regard to encephalitis have undergone considerable change in the past few years as a result of the intensive study of epidemic encephalitis. There are numerous references to involvement of the central nervous system during or shortly after an attack of measles. In most instances the authors apparently regarded these symptoms as incidental. Only rarely were the symptoms referable to the central nervous system grouped and designated as a definite clinical entity.

It has been recognized for a long time that the various acute infections, as measles, scarlet fever, pneumonia and pertussis, may be followed by encephalitis, most of which have manifested themselves in the form of a cerebral hemiplegia. Particular attention was called to these points by Abt1 in 1906. While we have seen a few instances of encephalitis following various of the acute