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May 14, 1927


JAMA. 1927;88(20):1579. doi:10.1001/jama.1927.02680460049018

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The Peculiar Effect of Ultraviolet Rays on the Cutaneous Reaction to Tuberculin  M. Carnot and his collaborators have made a strange discovery. When a skin reaction or an intradermal reaction to tuberculin is applied to a known tuberculous person and the region is afterward exposed to ultraviolet rays, no reaction is produced. It is not a question of an alteration of the tuberculin, for tuberculin remains intact after a prolonged exposure to ultraviolet rays. The failure to react would appear to be due to a modification of the physiology of the skin, which, after the use of ultraviolet rays, loses its power of reaction. The effect produced is the same if the irradiation has preceded the introduction of the tuberculin.

The Hereditary Transmission of Cancer  M. Auvray has reported a peculiar instance of the occurrence of cancer in the same family in four successive generations, the form of the disease

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