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Comment & Response
November 17, 2015

Dietary Cholesterol and Blood Cholesterol Concentrations—Reply

Author Affiliations
  • 1Friedman School of Nutrition Science and Policy, Tufts University, Boston, Massachusetts
  • 2New Balance Foundation Obesity Prevention Center, Boston Children’s Hospital, Boston, Massachusetts

Copyright 2015 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.

JAMA. 2015;314(19):2084-2085. doi:10.1001/jama.2015.12604

In Reply We agree with Ms Levin and colleagues that, after decades of misguided focus on dietary fat reduction, a “bewildered public” has trouble differentiating dietary cholesterol from blood cholesterol or cholesterol from saturated fat. Unfortunately, similar errors are sometimes made by scientists and policy makers when they do not differentiate between total blood cholesterol, LDL cholesterol, apolipoprotein B, other lipid and lipoprotein effects, nonlipid mechanistic pathways, or—most relevantly—risk of clinical cardiovascular events.

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