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In Reply We agree with Ms Levin and colleagues that, after decades of misguided focus on dietary fat reduction, a “bewildered public” has trouble differentiating dietary cholesterol from blood cholesterol or cholesterol from saturated fat. Unfortunately, similar errors are sometimes made by scientists and policy makers when they do not differentiate between total blood cholesterol, LDL cholesterol, apolipoprotein B, other lipid and lipoprotein effects, nonlipid mechanistic pathways, or—most relevantly—risk of clinical cardiovascular events.
Mozaffarian D, Ludwig DS. Dietary Cholesterol and Blood Cholesterol Concentrations—Reply. JAMA. 2015;314(19):2084–2085. doi:10.1001/jama.2015.12604
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