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Article
May 21, 1927

PHOSPHATURIA AS A LOCAL PHENOMENON: PRELIMINARY COMMUNICATION

JAMA. 1927;88(21):1625-1626. doi:10.1001/jama.1927.02680470011005
Abstract

For many years phosphaturia and its explanation has been somewhat baffling to clinicians, and there has been a decided tendency to ascribe this phenomenon of milky urine due to phosphates to some kind of metabolic disturbance or diathesis. During the last eight or nine years I1 have had the opportunity to make a number of observations on phosphaturic patients which suggest that this phenomenon is a peripheral and local one rather than due to any particular metabolic disturbance.

In the study of phosphatic urine, Lichwitz and others have called attention to the fact that a lipoid colloid separates from the urine as the urine becomes the milky urine of phosphaturia. On the other hand, if urines containing phosphates approach the alkaline reaction, dibasic calcium phosphate, tribasic calcium phosphate and dibasic magnesium phosphate precipitate out and produce a phosphaturic turbidity. As certain diets (vegetable, fruit and alkali) produce an excess

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