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February 8, 1941


JAMA. 1941;116(6):532. doi:10.1001/jama.1941.02820060080024

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To the Editor:—  An extensive experience in the management of acute appendicitis during the World War led to the publication of an article entitled "Immediate Surgical Management of Acute Appendicitis in Military Hospitals" (Surg., Gynec. & Obst.28:303 [March] 1919), suggesting a possible relationship between the onset of this condition in those cases in which there is a history of previous attacks and the method of administering the triple typhoid vaccine.In view of the fact that a new army is being inducted into service, it seems to me that this article carries some conclusions that may be of importance, especially to the younger medical officers of the army. I would therefore call special attention to the lowering of the white blood cell count following the administration of triple typhoid vaccine, with a lower white cell count at the onset of an attack of acute appendicitis.The blood picture

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