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February 15, 1941


JAMA. 1941;116(7):645. doi:10.1001/jama.1941.02820070095027

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To the Editor:—  Between January 1936 and January 1941 we have had 82 pregnant diabetic patients on whom hormonal studies have been done. Among our 12 consecutive abnormal untreated patients fetal survival was 42 per cent; among 35 consecutive abnormal but treated, as described in my paper, 89 per cent; among 35 normal diabetic patients 91 per cent. In the light of these figures we are unwilling to increase the number of untreated abnormal patients.Perhaps clarity in the matter of controls was sacrificed for brevity in the article which appeared in The Journal. I myself can see no scientific difference between the selection of alternate patients for therapy and of patients selected as in this work, namely, (1) 12 consecutive abnormal patients untreated, (2) 13 consecutive abnormal patients treated in the matter outlined by the Smiths, (3) 11 consecutive abnormal patients treated with oral preparations, (4) 11 consecutive abnormal

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