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May 28, 1927


JAMA. 1927;88(22):1747. doi:10.1001/jama.1927.02680480057030

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To the Editor:  —I have read with great interest "A Contribution to Helminthic Therapy," by M. Fernán-Núñez (The Journal, March 19).Dr. Núñez's results represent a careful study which is concisely and attractively presented. I am in accord with all his conclusions, but feel that Conclusion 6 should be amplified. He states that:Oil of chenopodium by intramuscular or intravenous injection is specific against Trichocephalus and Oxyuris, the two most difficult nematodes to eliminate.The drug is specific for these parasites if given intravenously or intramuscularly, but it is also very toxic.We have been using oil of chenopodium for about ten years in the treatment of helminthiasis and have studied this drug carefully. Since the drug is so specific in its action on nematodes, Pessoa and I, working in Brazil, hoped that it might be possible to use the drug in the treatment of parasitic nematodes that invade the

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