Whether normal kidney tissue will permit the passage of tubercle bacilli from the body into the urine is a matter of utmost importance, and to answer this question conclusively is the aim of this report.
If it can be proved that the tubercle bacillus does not pass through the normal kidney, the following points are of value to the practicing physician and to the patient:
First, if a given patient has had tubercle bacilli in the urine at any time, as demonstrated by guinea-pig inoculation, and such a person comes to autopsy, the absence of a tuberculous lesion in the kidney or any other part of the genital or urinary tracts would be good evidence to show that tuberculosis of the kidney could heal spontaneously. And if this occurred often enough to preclude the probability of error, it would be proof of such spontaneous healing. Until this work is done
SPITZER WM, WILLIAMS WW. DOES NORMAL KIDNEY TISSUE PERMIT THE PASSAGE OF TUBERCLE BACILLI? JAMA. 1927;88(24):1870–1872. doi:10.1001/jama.1927.02680500012005
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