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Featured Clinical Reviews

December 22/29, 2015

Repeated In Vitro Fertilization Cycles for Infertility

Author Affiliations
  • 1Department of Obstetrics and Gynecology and Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina
JAMA. 2015;314(24):2627-2629. doi:10.1001/jama.2015.17297

Infertility has traditionally been defined as failure to achieve pregnancy after 12 months of regular unprotected intercourse with the same partner; because approximately half of these couples will conceive without intervention over the next 12 to 24 months, the term subfertility is also sometimes used.1 Self-reported infertility, using the 12-month definition, affected approximately 6% of married women aged 15 to 44 years in the 2006-2010 National Survey of Family Growth (the most recent available data).2 There are a number of etiologies for subfertility in both women and men,3,4 and treatments directed at specific causes, such as anovulation secondary to polycystic ovary syndrome, can be effective.5

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