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June 18, 1927


Author Affiliations

San Francisco.

JAMA. 1927;88(25):1983. doi:10.1001/jama.1927.02680510041023

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To the Editor:  —I was much interested in the editorial (The Journal, May 14, p. 1571), on "The Injection Treatment of Varicose Veins," which reported Lomholt's fatal case of pulmonary embolism. I have successfully treated more than a hundred patients by the injection method in the last five years, and have always assumed that embolism was a mechanical impossibility in these cases on account of the extreme toughness and firm adherence of the chemically induced thrombi.The extreme degree and persistence of the acute inflammatory reaction in the injected veins in Lomholt's case suggests that the thrombi had become infected by pyogenic bacteria in the blood stream, perhaps from abscessed teeth or other foci. I have always insisted on the eradication of all foci of infection before injecting any varicose veins, and my occasional neglect of this precaution has usually been followed by a severe inflammatory reaction. Possibly, Lomholt followed

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