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Comment & Response
January 12, 2016

Tinzaparin vs Warfarin for Acute Venous Thromboembolism

Author Affiliations
  • 1Department of Pharmaceutical Sciences, University of British Columbia, Vancouver, Canada
  • 2Therapeutics Initiative, University of British Columbia, Vancouver, Canada

Copyright 2016 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.

JAMA. 2016;315(2):200. doi:10.1001/jama.2015.15067

To the Editor Primary results from the Comparison of Acute Treatments in Cancer Hemostasis (CATCH) trial1 were reported as negative, but the authors found an association between tinzaparin use compared with warfarin and reduction in the secondary outcome of clinically relevant nonmajor bleeding. Analysis of serious adverse events and mortality from this trial leads us to question the authors’ overall conclusions.

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