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April 5, 1941

Current Comment

JAMA. 1941;116(14):1527-1528. doi:10.1001/jama.1941.02820140039012

SULFATHIAZOLE CONTAMINATED WITH PHENOBARBITAL—A WARNING  The contamination of a considerable amount of sulfathiazole, manufactured by the Winthrop Chemical Company, with phenobarbital—luminal—and its widespread distribution throughout the United States was widely reported in the press and on the radio on March 28. Information first received indicated that only one lot of the product, marked MP 029, was contaminated and all of it was distributed in bottles containing 100, 500 or 1,000 tablets each weighing 0.5 Gm. None of this material was reported to have been distributed along the Pacific Coast. Approximately 410,000 tablets were distributed, and approximately 118,000 tablets were still in circulation on March 20. In the Chicago area only bottles containing 500 tablets were distributed. Word just received, however, indicates that lot MP 118 may also be involved. Of this lot there were 110 bottles containing 100 tablets each. This lot was distributed between December 18 and December 25