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April 19, 1941


JAMA. 1941;116(16):1867. doi:10.1001/jama.1941.02820160119022

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To the Editor:—  In the March 1 issue of The Journal is a communication from Alfred Gilman, Ph.D., of Yale University, objecting on theoretical grounds to the use of adrenal cortex extract in the treatment of bromide intoxication as described by Bondurant and Campbell in the January 11 issue of The Journal. As adrenal cortex extract has been advocated by these authors, I would like to substantiate Dr. Gilman's theoretical objection by reporting that 5 patients with bromide intoxication, each treated with a total of 35 mg. of adrenal cortex extract and salt, failed to recover more rapidly than the usual patient treated by salt alone.The most rapid method of eliminating bromides still seems to be by gastric lavage of the hydrobromic acid secreted by the stomach.

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