The manifestations in many general conditions, as revealed by the ocular fundus, have been analyzed as to type and incidence on a comparative basis. These tabulations are of the greatest benefit to the ophthalmologist in aiding the internist and surgeon in diagnosis and prognosis.
The toxemias are treated separately in the literature, although there are certain signs that are common to all. They are all acute infectious processes with many fundamental pathologic similarities. Since the toxemias quickly showed generalized symptoms, it was thought that the eyegrounds might be seen to participate more or less uniformly if a sufficient number of cases of all types were studied. To this end, the eyes of every patient admitted to the medical wards of the Cincinnati General Hospital were examined as a matter of routine. Only the fundus observations in the acute toxemias are considered here. The word "lesion" henceforth will refer only to
BROWN AL. THE OCULAR FUNDUS IN THE ACUTE TOXEMIAS: AN ANALYSIS OF EIGHT HUNDRED AND FIFTY CASES. JAMA. 1927;89(3):174–177. doi:10.1001/jama.1927.02690030006004
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